Osteosarcomatous De-differentiation of Low Grade Chondrosarcoma of Mandible –A Clinical Rarity

Introduction: Chondrosarcoma is a malignant cartilaginous tumour arising de novo in a bone or superimposed upon a pre – existing benign cartilaginous neoplasm. It makes up 10 % of malignant tumours of jaws. Case report: A case of de-differentiated chondrosarcoma of the anterior region of the mandible is presented, which was initially low grade variant and on recurrence it was turned to be a high grade variant of osteosarcomatous type with metastasis to lungs, along with a review of its prognostic factors. Conclusion: When occurring in the head and neck, it arise most frequently in the maxilla, less common sites of involvement are the mandibular body, symphysis, coronoid process and condylar processes. Recurrent tumour always forecast bad prognosis.